Mater marks four decades of life-saving transplants
Padraig Conlon 18 Sep 2025
Forty years ago, in a Dublin operating theatre, a team of pioneering surgeons took a leap into the unknown that would change Irish medicine forever.
On September 10, 1985, doctors at the Mater Misericordiae University Hospital carried out Ireland’s very first heart transplant, giving a young man a second chance at life and paving the way for hundreds more to follow.
Last week the Mater celebrated that historic milestone. Since that ground-breaking operation, its National Centre for Heart and Lung Transplants has performed 447 life-saving heart transplants, a programme that has transformed the lives of patients and their families and cemented the hospital’s place at the heart of Irish healthcare.
It was the determination of two visionary surgeons, Mr Maurice Nelligan and Prof Freddie Wood, that brought the idea of heart transplantation to Ireland at a time when it was still a rarity worldwide.
Together, they laid the foundation for a programme that has endured for four decades and remains a beacon of medical progress.
Among the earliest patients was Andy Kavanagh, who underwent his transplant in 1986 at just 19 years of age. Only a year earlier, what seemed to be a simple flu had developed into cardiomyopathy, a devastating disease that attacked his heart muscles.
With his health rapidly deteriorating, his only chance of survival was to undergo what was then a brand-new procedure for Ireland.
“I was very sick before my transplant. It was a risk at the time, taking a chance on something that was so new in Ireland,” Andy recalled this week.
“Thankfully, the team at the Mater gave me that option. Today, nearly four decades later, I am doing great, working full-time, going to the gym daily and living a full and active life.”
Andy’s story is remarkable not only for its survival against the odds but also for its longevity. He is now recognised as one of the longest surviving heart transplant patients in the world.
For Prof Freddie Wood, who led his surgery, it is living proof of what was achieved in those early days.
“When we carried out the first transplant, we didn’t know what the long-term outcomes would be. To see patients not only survive but thrive for decades after is extraordinary,” he said.
Behind every successful transplant lies an act of immense generosity.
The Mater’s 447 operations have only been possible through the courage of organ donors and their families. Prof Emer Joyce, Consultant Cardiologist at the Mater, highlighted the vital role donation continues to play. “For many patients, organ donation is their only hope,” she said.
“Forty years ago, a heart transplant was a leap into the unknown.
Today, the prognosis is much better. Transplants are a proven treatment that have restored health to generations of patients.
None of this would be possible without the courage of donors and their families. Organ donation saves lives.”
The Mater has also continued to lead innovation in advanced heart therapies. In 2009 it became the first Irish hospital to introduce durable left ventricular assist devices, or LVADs, which act as mechanical pumps to support failing hearts.
Since then, 34 patients have benefitted from LVADs as part of their treatment.
The hospital is also a national centre for extracorporeal membrane oxygenation, or ECMO, which provides temporary life support for patients in severe heart or lung failure.
These advances, alongside transplantation, have given hope and extra years to countless patients who otherwise would not have survived.
The impact of these treatments goes far beyond the hospital ward. Patients have been able to return to work, to raise families, and in some cases to represent Ireland at the international Transplant Games.
For many, what once seemed like a medical miracle has become the beginning of a new chapter.
Marking the 40th anniversary last Wednesday (10th), Mater Hospital CEO Josephine Ryan Leacy paid tribute to the staff, patients, and families who have all been part of the journey.
“Today is a wonderful day to recognise and celebrate the impact of heart transplantation in Ireland. Since 1985, the Mater’s heart transplant teams have given hundreds of people a second chance at life and the opportunity to spend more precious time with their families and loved ones.
“The Mater Hospital is proud of our legacy in transplantation and we remain committed to growing the programme and advancing care for the next generation of patients.”
What began with one bold decision on a September day in 1985 has grown into a national service that continues to save and transform lives.
Forty years on, the legacy of Ireland’s first heart transplant at the Mater is not only measured in numbers but in the living, breathing proof of people like Andy Kavanagh, whose lives were rewritten by the gift of a new heart.